Tracking and Improving Bedside Procedures Through Standardized Documentation

Proposal and Goals: We propose to create a standardized electronic procedure note that will replace all documentation for bedside procedures without sedation. ◦Makes notes legible and easily identified ◦Allows uniform tracking of metrics necessary to identify outcomes from a procedure (blood loss, specimens, post-procedure studies, complications) 2.The procedure note will be created in such a way as to allow specialized procedures to be added over time with minor customization to improve physician/nursing work flows and increase efficiency ◦Allows procedures to be sorted and tracked by type ◦Will be constructed to allow attaching CPT codes to patient charts via documentation 3. We propose using this procedure note to create a running database of all bedside procedures ◦Can be utilized by existing software (Qlik) to query all procedure notes to create large anonymized patient listshttps://jdc.jefferson.edu/patientsafetyposters/1071/thumbnail.jp

Spontaneous, collective coherence in driven, dissipative cavity arrays

We study an array of dissipative tunnel-coupled cavities, each interacting with an incoherently pumped two-level emitter. For cavities in the lasing regime, we find correlations between the light fields of distant cavities, despite the dissipation and the incoherent nature of the pumping mechanism. These correlations decay exponentially with distance for arrays in any dimension but become increasingly long ranged with increasing photon tunneling between adjacent cavities. The interaction-dominated and the tunneling-dominated regimes show markedly different scaling of the correlation length which always remains finite due to the finite photon trapping time. We propose a series of observables to characterize the spontaneous build-up of collective coherence in the system.Comment: 9 pages, 4 figures, including supplemental material (with 4 pages, 1 figure). This is a shorter version with some modifications in the supplemental material (a gap in the proof was closed and calculations significantly generalized and improved

Both Chromosome Decondensation and Condensation Are Dependent on DNA Replication in C.elegans Embryos

SummaryDuring cell division, chromatin alternates between a condensed state to facilitate chromosome segregation and a decondensed form when DNA replicates. In most tissues, S phase and mitosis are separated by defined G1 and G2 gap phases, but early embryogenesis involves rapid oscillations between replication and mitosis. Using Caenorhabditis elegans embryos as a model system, we show that chromosome condensation and condensin II concentration on chromosomal axes require replicated DNA. In addition, we found that, during late telophase, replication initiates on condensed chromosomes and promotes the rapid decondensation of the chromatin. Upon replication initiation, the CDC-45-MCM-GINS (CMG) DNA helicase drives the release of condensin I complexes from chromatin and the activation or displacement of inactive MCM-2–7 complexes, which together with the nucleoporin MEL-28/ELYS tethers condensed chromatin to the nuclear envelope, thereby promoting chromatin decondensation. Our results show how, in an early embryo, the chromosome-condensation cycle is functionally linked with DNA replication

Polarons in semiconductor quantum-dots and their role in the quantum kinetics of carrier relaxation

While time-dependent perturbation theory shows inefficient carrier-phonon scattering in semiconductor quantum dots, we demonstrate that a quantum kinetic description of carrier-phonon interaction predicts fast carrier capture and relaxation. The considered processes do not fulfill energy conservation in terms of free-carrier energies because polar coupling of localized quantum-dot states strongly modifies this picture.Comment: 6 pages, 6 figures, accepted for publication in Phys.Rev.

Study of flight management requirements during SST low visibility approach and landing operations. Volume 1 - Definition of baseline SST landing system

Baseline instrument landing system for low visibility approach and landing of supersonic transport

Parvovirus B19 infection in pediatric transplant patients

Evidence of recent parvovirus virus infection (as determined by the presence of a positive IgM antibody titer) without other identified causes of anemia was found in 5 of 26 pediatric solid-organ transplant recipients evaluated for moderate-to-severe anemia between June 1990 and July 1991. Anemia tended to be chronic (median duration of anemia at the time of diagnosis was 12 weeks) and was associated with normal red blood cell indices in the absence of reticulocytes. The median age of the children at the time of presentation with anemia due to parvovirus was 1.8 years at a median time of 8 months after transplantation. Four of the 5 children were treated with i.v. immunoglobulin because of persistance of anemia requiring blood transfusions. A response characterized by an increase in reticulocyte count and normalization of hemoglobin was seen in each of these patients 2-4 weeks after treatment. The remaining patient experienced a spontaneous recovery from her anemia. Parvovirus infection should be included in the differential diagnosis of solid-organ transplant recipients presenting with severe anemia associated with low or absent reticulocytes